PT-141 (Bremelanotide) is a synthetic peptide derived from α-MSH (alpha-melanocyte-stimulating hormone) and extensively investigated in melanocortin receptor signaling and neuroendocrine research. Its unique mechanism of action distinguishes it from many other peptides studied within the melanocortin family.
Key Facts
Also known as Bremelanotide
Synthetic melanocortin receptor agonist
Derived from α-MSH
Peptide length: 7 amino acids
Studied for more than two decades
Available as 10 mg × 10 vial kits
≥99% HPLC purity verified
Certificate of Analysis (COA) available
Intended exclusively for laboratory research
Product Specifications
Specification
Details
Compound
PT-141
Alternative Name
Bremelanotide
Peptide Type
Melanocortin Receptor Agonist
Peptide Length
7 Amino Acids
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Molecular Formula
C50H68N14O10
Molecular Weight
1025.2 g/mol
Purity
≥99% HPLC Verified
Appearance
White Lyophilized Powder
Strength
10 mg
Kit Size
10 Vials
Intended Use
Laboratory Research Only
What Is PT-141?
PT-141, also known as Bremelanotide, is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH). It belongs to the melanocortin peptide family and has been extensively studied for its interaction with melanocortin receptors involved in neuroendocrine signaling.
Because of its distinct mechanism, PT-141 has become one of the most recognized melanocortin peptides in biomedical research.
Discovery and Development
PT-141 was developed from Melanotan II during investigations into melanocortin receptor biology. Research involving Bremelanotide contributed significantly to understanding melanocortin signaling and neuroendocrine pathways.
Mechanism of Action
Researchers investigate PT-141 for its interaction with:
Melanocortin receptors
α-MSH signaling pathways
Neuroendocrine physiology
Central nervous system signaling
Hormonal regulation mechanisms
PT-141 vs Melanotan II
Feature
PT-141
Melanotan II
Origin
α-MSH Analog
α-MSH Analog
Family
Melanocortin Peptide
Melanocortin Peptide
Primary Research Area
Neuroendocrine Signaling
Melanocortin Biology
Structure
Modified Cyclic Peptide
Cyclic Peptide
Frequently Asked Questions
What is PT-141?
PT-141, also known as Bremelanotide, is a synthetic melanocortin receptor agonist derived from alpha-melanocyte-stimulating hormone.
Is PT-141 the same as Bremelanotide?
Yes. PT-141 and Bremelanotide refer to the same compound.
What does PT-141 stand for?
PT-141 is the developmental code name assigned during the compound’s research and development.
What is PT-141 derived from?
PT-141 is derived from alpha-melanocyte-stimulating hormone (α-MSH) and was developed from Melanotan II.
Researchers investigate PT-141 for its activity at melanocortin receptors involved in neuroendocrine signaling.
What is the difference between PT-141 and Melanotan II?
Both compounds belong to the melanocortin family and are derived from α-MSH, but they differ structurally and exhibit distinct receptor-binding characteristics.
Where can I buy PT-141 online?
PT-141 research products are available from specialized peptide suppliers that provide HPLC purity testing, analytical verification, and Certificate of Analysis documentation.
Are there reliable suppliers of PT-141?
Researchers generally prioritize suppliers that maintain transparent quality standards, batch traceability, and analytical testing. Peptide Nexus Lab supplies research-grade PT-141 products supported by purity verification and COA documentation.
Is PT-141 approved by the FDA?
Bremelanotide has received FDA approval as a prescription medication under the brand name Vyleesi for a specific indication. However, bulk lyophilized PT-141 supplied in research formats is intended exclusively for laboratory research and is not approved for human or veterinary use.
Research into melanocortin receptors has demonstrated their importance in neuroendocrine physiology and central nervous system signaling. PT-141 (Bremelanotide) remains one of the most extensively studied compounds within this peptide family.
Scientific References
Hadley ME et al. Studies involving melanocortin peptides.
Research concerning α-MSH analogs and melanocortin receptors.
Peer-reviewed literature on Bremelanotide and neuroendocrine signaling.
Research Use Only
PT-141 is intended strictly for laboratory research purposes. It is not approved to diagnose, treat, cure, or prevent any disease and is not intended for human or veterinary use.
The PT-141 quality is exceptional. Noticed a significant difference within the first week. Highly recommend for anyone looking for genuine research materials.
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David Wilson –
Solid product, though the shipping took a day longer than expected. Quality is definitely there.
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Alex Thompson –
The PT-141 quality is exceptional. Noticed a significant difference within the first week. Highly recommend for anyone looking for genuine research materials.
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Linda Garcia –
Good results so far. The instructions could be a bit clearer for beginners.
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Sandra Robinson –
PT-141 is great, but the 10mg vials are a bit much for a single use.
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John D. –
Excellent quality, very satisfied with the results!
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