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Ipamorelin is a synthetic growth hormone secretagogue peptide supplied for laboratory and scientific research applications. Widely studied for its selective stimulation of growth hormone release, Ipamorelin is of interest in research involving metabolism, cellular function, and recovery-related processes. Manufactured to high purity standards, it is intended for controlled and consistent research use.
When modeling growth hormone (GH) pulsatility in vitro or in vivo, maintaining baseline metabolic stability is critical. Older secretagogues like GHRP-2 or GHRP-6 trigger GH release, but they severely compromise experimental data by simultaneously spiking cortisol and prolactin, while inducing severe lipogenesis (extreme hunger). Ipamorelin solves this problem. As the most selective GH secretagogue available, it isolates the GH pulse without elevating stress hormones or corrupting metabolic baselines.
If your laboratory investigates cellular regeneration, bone mineral density, lipolysis, or age-related endocrine decline, Ipamorelin is the definitive peptide for clean, highly targeted growth hormone signaling. With this 10-vial, 20mg kit, you secure enough highly stable, analytical-grade pentapeptide to run rigorous, longitudinal assays without batch-to-batch variance.
What you get in this kit:
2mg per vial (10 vials total = 20mg)
≥99% HPLC purity with a verifiable Certificate of Analysis (COA)
Maximum structural stability for complex endocrine models
36-month lyophilized shelf life
What Is Ipamorelin Peptide?
Ipamorelin (CAS: 170851-70-4) is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) designed to function as a potent, highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR).
Unlike exogenous synthetic HGH, which blunts the body’s natural production via a negative feedback loop, Ipamorelin stimulates the pituitary gland to release endogenous GH in a natural, pulsatile manner. It achieves this while demonstrating practically zero affinity for lipogenic receptors or ACTH (adrenocorticotropic hormone) pathways. This hyper-selectivity ensures that your data reflects purely the downstream effects of growth hormone and IGF-1 (Insulin-like Growth Factor 1) upregulation, free from the noise of acute stress responses.
Primary Research Applications
Endocrinology & GH Pulsatility: Used extensively as a baseline control to model natural, age-appropriate growth hormone restoration without downregulating native pituitary function.
Bone Mineral Density (BMD): Investigated for its capacity to stimulate osteoblast proliferation and accelerate the mineralization of bone tissue in simulated osteoporosis models.
Muscle Regeneration & Nitrogen Retention: Frequently utilized in soft tissue recovery models to observe the accelerated repair of myofibers and increased cellular nitrogen retention following simulated trauma.
Lipid Metabolism: Studied for its role in modulating lipolysis (fat oxidation) without triggering the ghrelin-induced hunger response that skews metabolic caloric intake in animal models.
Kit Specifications
Detail
Specification
Compound
Ipamorelin Acetate
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2
Chemical Formula
C38H49N9O5
Molar Mass
711.86 g/mol
CAS Number
170851-70-4
Purity
≥99% HPLC verified
Kit Configuration
10 vials × 2mg = 20mg total
Physical Form
White Lyophilized Solid
Intended Use
In vitro laboratory research only
Reconstitution & Storage Guide
Protect your 36-month shelf-life investment. Proper handling is non-negotiable for preserving the five-amino-acid chain structure.
Temperature Acclimation: Remove the vial from cold storage 10–15 minutes before starting to prevent uneven dissolution.
Sterilize the Stopper: Wipe the rubber stopper with a 70% IPA swab and wait 30 seconds for it to dry. Do this every single time you draw from the vial.
Controlled Injection: Draw your bacteriostatic water. Angle the needle so the solvent runs slowly down the inner glass wall. Do not blast the powder directly, which causes structural shearing.
Swirl Gently (Never Shake): Roll the vial slowly between your palms in a circular motion until the liquid is perfectly clear. Do not shake. Shaking irreversibly damages the peptide structure.
Refrigerate: Store upright at 2°C to 8°C. Use within 21 to 28 days. Keep away from direct UV exposure.
FAQs About Ipamorelin Peptide
How does Ipamorelin differ from GHRP-6 and GHRP-2?
While all three are GH secretagogues, GHRP-2 and GHRP-6 also stimulate the release of cortisol and prolactin, and GHRP-6 triggers extreme hunger. Ipamorelin is clinically noted for being “cleaner”—it strictly stimulates GH release without elevating stress hormones or significantly impacting appetite, making it vastly superior for controlled metabolic research.
Can Ipamorelin be stacked with other peptides in research models?
Yes. In advanced endocrine models, it is almost exclusively paired with a GHRH (Growth Hormone Releasing Hormone) analog, such as CJC-1295 (No DAC). The GHRH sets the “floor” of the GH pulse, while the secretagogue (Ipamorelin) sets the “ceiling,” resulting in a highly synergistic, amplified pulse.
Does Ipamorelin shut down natural HGH production?
No. Because it acts as an agonist at the ghrelin receptor to stimulate natural pituitary function, it does not bypass the body’s natural regulatory systems or cause the negative feedback loop associated with exogenous recombinant HGH administration.
Are there any approved drugs containing Ipamorelin?
No. Bulk lyophilized Ipamorelin remains an investigational compound. It holds no FDA, EMA, or Health Canada approval for clinical injection, oral consumption, or systemic therapeutic administration.
⚠️ Research Use Only: Ipamorelin Peptide is intended strictly for in vitro laboratory research and in vivo testing by qualified professionals. Not for human or veterinary consumption. Not evaluated or approved by the FDA, EMA, or Health Canada.
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James Anderson –
Ipamorelin is very pure. Great for my growth hormone research.
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Patricia Thomas –
Solid product. Shipping was fast and discreet.
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Michael Brown –
Ipamorelin is great. Purity is top-notch.
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